RI’s expertise in optics and micromanipulation allows us to offer a carefully chosen package for Intracytoplasmic Morphologically-selected Sperm Injection (IMSI) which provides excellent image quality yet remains simple and practical for routine clinical use, without unnecessary expense.
Compatible with the Integra 3™ micromanipulators and featuring high resolution air objectives and a high quality camera and monitor, RI IMSI™ is the ultimate IMSI solution. It offers great image quality whilst remaining easy and quick to use for clinical IMSI.
The RI IMSI™ solution allows morphological screening of sperm cells at very high magnification and in real time. Studies suggest that this can lead to higher pregnancy rates1,2,3.
The RI IMSI™ package has been designed for quick and easy routine clinical use, with the same microscope that you use for ICSI, thus maximising the benefit of the technique. Standard plastic dishes can be used, removing the need to transfer between dishes, and saving time and money.
We supply an imaging package including a high-sensitivity camera, medical-grade monitor and versatile imaging software. Working with Modulation Optics Inc., RI have developed a unique, highly sensitive optical system with a 60x objective ensuring a high-resolution source image.
Our digital camera (the DC2) has been specifically designed for IMSI imaging. The large sensor has high-sensitivity pixels for bright, high-contrast images.
We supply a top quality medical-grade monitor which offers colour depth and accuracy vastly superior to standard PC monitors, and is perfect for accurately reproducing the subtle details in moving sperm images.
RI IMSI™ is supplied with the easy to use Cronus 3™ software – the only application you need for ICSI and IMSI. Capture, record, annotate and measure, with intuitive zoom and pan.
1Bartoov, B et al, 2002. Real-Time Fine Morphology of Motile Human Sperm Cells is Associated With IVF-ICSI Outcome, Journal of Andrology,Vol. 23, No. 1, January/February 2002
2Cassuto, N et al, 2009. A new real-time morphology classification for human spermatozoa: a link for fertilization and improved embryo quality, Fertility and Sterility, Vol. 92, No. 5, November 2009
3Kim, H.J. et al., 2014. Comparison between intracytoplasmic sperm injection and intracytoplasmic morphologically selected sperm injection in oligo-astheno-teratozoospermia patients. Clinical and experimental reproductive medicine, 41(1), pp.9–14. Available at: http://synapse.koreamed.org/DOIx.php?id=10.5653/cerm.2014.41.1.9
RI IMSI Brochure (704.9 KiB, 0 hits)
Hardware Brochure (3.4 MB, 0 hits)
Product Catalogue (5.6 MB, 0 hits)
IMSI Research Paper 2014 (621.6 KiB, 0 hits)
Q: Won’t a 2MP/5MP camera give a better image?
A: No. Our 1.4MP cameras offer the optimum balance between resolution, contrast and noise. A higher resolution camera cannot improve the resolution available from the microscope, and will actually give a poorer quality image.
Q: Why don’t you offer a zoom C-mount?
A: They are expensive, only allow zooming to a fixed point, and only add empty magnification without improving resolution. Image manipulation using the software is much more flexible.
Q: Can I use my existing Nikon NAMC/Olympus RC condenser?
A: In many cases, yes. We can offer 60x objectives to suit compatible condensers, but image resolution may be lower than with a complete HMC system. Contact us with details of your system and we will advise.
Q: Do I have to use glass dishes and messy immersion oil?
A: No. Our system uses air objectives which work with standard plastic dishes.