The Integra Ti™ is accurate, simple to use and reliable. It has been designed to offer the ultimate in user control. Simple pipette set-up and angle adjustment reduce the time of ICSI procedures, therefore optimising results.
The Integra Ti™ is the ultimate micromanipulation workstation and, when coupled with RI’s high commitment to after-sales service, offers an unbeatable package.
Specimen temperature control
The Integra Ti has a unique temperature control system – accurate to 0.1ºC. Separate channels control the central stage insert and two additional areas, for extra Petri dishes.
Controlled by a touch screen, you can be confident of the most accurate temperature control available today.
Heated glass insert
In addition to the standard metal heated insert, the Integra Ti has the option of an RI or Tokai Hit heated glass insert. Using the latest ITO technology, heat is evenly distributed over the entire surface of the Petri dish, eliminating the central cold spot.
The Integra Ti uses a built-in XY mechanical stage for manipulation of the Petri dish.
The Integra Ti comes with two syringes included as standard. We offer both air and oil syringes with this system. Our very popular SAS air syringes give superb control and eliminate the need for oil. Our new SOS oil syringe is now available with a quick fill feature to reduce set-up time.
The toolholders provide the simplest and quickest method ever for setting-up micropipettes. The toolholders, when used with a special objective and spacer (supplied), allow the micropipettes to be set-up 14mm above the Petri dish and then rapidly lowered to the desired position, preventing micropipette damage. The toolholders also have a special angular adjustment which allows the user to adjust the angle of the pipette with a single control without moving the tip of the pipette. Unique to RI, this feature makes it easy to ensure that the micropipette is slightly “toe-down” during sperm immobilisation and horizontal during sperm injection. This reduces the damage caused to the oocyte and therefore increases its chances of survival and hence development. For PGD, RI has developed a unique double toolholder which offers independent movement of both micropipettes.
Movement of the micropipettes is provided by RI’s exceptional TDU5000 micromanipulators, offering the most accurate and precise positioning available. Each micromanipulator offers both fine and coarse ZYX control and comes with our latest range of toolholders. The TDU5000s are extremely reliable and rarely require servicing. Being purely mechanical they do not suffer from delay as in electronic micromanipulators or lost motion and drift common in hydraulic systems.
Q: What are the advantages of the Integra Ti™ over Narishige and Eppendorf?
A: The Integra Ti™ gives the user a natural movement with no delays from hydraulics or motors.
It has a much quicker and easier pipette set-up procedure with instant angle changer.
It is more compact and gives more lab space, whilst providing a larger stage surface area to work on.
Three accurate, built-in, heated stage inserts to provide stable temperature during micromanipulation with Glass insert option.
Air syringes are supplied as standard giving excellent control.
RI provides excellent technical support for repairs and servicing of equipment, which Narishige, as part of the Company Policy, do not.
It is mechanical in design, and by its very nature, has a reliability and longevity far-surpassing any electrical or hydraulic equipment.
Q: How easy is it to change over to RI if I’ve never used it before?
A: Very easy – most people convert perfectly after a couple of sessions. You have to get used to the new positions that your hands need to be in and get used to the control of the air syringes, but it takes very little time and once mastered, the control is superb and the operation much quicker.
Q: What if we don’t wish to use the air syringes?
A: We can supply our own high quality oil syringes, and we have even been able to incorporate the customers existing syringes into the Integra Ti™ system.
Q: Can RI provide training?
A: We can show how to use the equipment on installation, or we can arrange a training session either at a current users’ lab, or get an experienced embryologist to your lab at your cost.
Q: Is there anything that the Integra Ti can’t do that the others can?
A: The RI system does not have an x-axis lock that other systems use for injection. However, after they start to use the Integra Ti, all our customers find that an x-lock is unnecessary as they can inject perfectly without it.
Q: What comes with the system?
A: The Integra Ti™ comes as standard with:
Integra Stage Unit
Toolholders with Automatic pipette set-up
3 x Heated stage inserts
Coarse and fine micromanipulators
2 x Syringes / Injectors
2 x Hand-rests
x-y mechanical stage
Digital Help Menu
Glass heated stage insert
Extra-smooth air syringe
PC / monitor
RI Viewer™ imaging software
Q: Which microscopes will it fit to?
A: Nikon TMD, D200/300, TE200/300, TE2000, TI
Olympus IMT2, IX50/70, IX51/71, IX53/73/83
Zeiss Axiovert 40, 200, Axio Observer
Leica DMIRB, DMI3000B/4000B/6000B, DMIL
Q: How does it compare in price?
A: The Integra Ti™ is normally much better value for money than the Eppendorf system and competitive with the Narishige system, although will sometimes be more expensive. However, remember that you’re getting the syringes, 3 x heated inserts, the x-y mechanical stage and the automatic pipette set-up included which sometimes don’t appear on competitors’ quotes, and you can also have the reassurance that RI care about their customers and understand the often urgent needs of the IVF Industry. Also, you’re getting equipment that is mechanical in design, and by its very nature, has a longevity far-surpassing any electrical or hydraulic equipment.